Senescence Markers: One is not Good Enough, We Need More!

One is not enough.

In both prokaryotic and eukaryotic organisms, repressors and activators are responsible for regulating gene expression. The lac operon is a paradigm for understanding how metabolites function as signaling molecules and modulate transcription. These metabolites or allosteric effector molecules bind to the repressor and alter the conformational equilibrium between the induced and the repressed st...

Ramadan fasting: Do we need more evidence?

Over a billion of Muslims fast worldwide during Ramadan each year. Through this religious custom, fasting contributes to their health as well as their spiritual growth. However, available evidence regarding the health-benefits of Ramadan fasting is scarce and highly contentious. Although Islam exempts patients from fasting, many fast conceivably, and their clinical condition is prone to deterio...

Because good enough is never good enough

hsr Proceedings in intensive care and cardiovascular anesthesia 2012, Vol. 4 Corresponding author: Prof. Michael John Università Vita-Salute San Raffaele Via Olgettina, 48 20132 Milan, Italy e-mail: [email protected] And now for something completely different. Formula one racing drivers need to know the track they will be speeding around to avoid injuring themselves and others, and hopefully ...

More palliative care specialists is not enough.

When One Pipeline Is Not Enough

Pipelines that operate on buffers often work well to mitigate the high latency inherent in interprocessor communication and in accessing data on disk. Running a single pipeline on each node works well when each pipeline stage consumes and produces data at the same rate. If a stage might consume data faster or slower than it produces data, a single pipeline becomes unwieldy. We describe how we h...